Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28899614 | 1.00 | TSHR (0.47) | TSHRDNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL28899621 | 1.00 | TSHR (0.47) | TSHRDNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL29163705 | 1.00 | TSHR (0.47) | TSHRDNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL28899670 | 1.00 | TSHR (0.47) | TSHRDNM1HTTPLA2G1BHSP90AA1 | |
| SCHEMBL4602343 | 0.98 | TSHR (0.44) | TSHRDNM1HTTSLC22A1 | |
| Bromide SCHEMBL27620439 | 0.96 | DNM1 (0.45) | TSHRDNM1HTTHSP90AA1RAD52 | |
| Propylamine SCHEMBL2760772 | 0.93 | TSHR (0.42) | TSHRDNM1HTTPLA2G1BHSP90AA1 | |
| Hydrochloric Acid SCHEMBL8682761 | 0.84 | TSHR (0.35) | TSHR | |
| Hydrochloric Acid SCHEMBL2760773 | 0.83 | PAOX (0.41) | TSHR | |
| SCHEMBL17036766 | 0.81 | BBOX1 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385816-A | Fatty alkyl quaternary ammonium salt type antibacterial agent composite bone cement and preparation and application thereof | 上海应用技术大学 | 2022-11-25 | — | — | CN | disclosed |