Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4539279 | 0.90 | MAPT (0.38) | TXNRD1MAPTPKMCYP1A2CYP2C9 | |
| SCHEMBL22572955 | 0.88 | MAPT (0.33) | TXNRD1MAPTPKMMEN1KMT2A | |
| SCHEMBL2554448 | 0.83 | GPR35 (0.33) | TXNRD1MAPTCYP1A2MEN1KMT2A | |
| SCHEMBL22572956 | 0.80 | ALDH1A1 (0.34) | TXNRD1MAPTMEN1KMT2A | |
| SCHEMBL16416435 | 0.78 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL22090173 | 0.78 | TXNRD1 (0.36) | TXNRD1MAPTMEN1KMT2A | |
| SCHEMBL22557442 | 0.77 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL28900035 | 0.77 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL23012193 | 0.75 | CYP11B1 (0.35) | PRMT5WDR77 | |
| SCHEMBL22089936 | 0.73 | JAK2 (0.34) | TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115244055-A | Pyrimido five-membered ring derivative and application thereof | 江苏先声药业有限公司 | 2022-10-25 | — | — | CN | disclosed |