Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554448 | 0.88 | GPR35 (0.33) | TXNRD1LMNAALDH1A1TDP1 | |
| SCHEMBL22572956 | 0.82 | ALDH1A1 (0.34) | TXNRD1LMNAALDH1A1 | |
| SCHEMBL4539279 | 0.79 | MAPT (0.38) | TXNRD1LMNAALDH1A1 | |
| SCHEMBL22089675 | 0.76 | JAK2 (0.36) | JAK2JAK1TYK2JAK3PARP1 | |
| SCHEMBL22572955 | 0.73 | MAPT (0.33) | TXNRD1 | |
| SCHEMBL28899995 | 0.73 | TXNRD1 (0.34) | TXNRD1 | |
| SCHEMBL22090173 | 0.71 | TXNRD1 (0.36) | TXNRD1ALDH1A1 | |
| SCHEMBL28313397 | 0.71 | TSHR (0.46) | LMNAALDH1A1TDP1 | |
| SCHEMBL24791181 | 0.70 | JAK2 (0.36) | JAK2JAK1TYK2JAK3TXNRD1 | |
| SCHEMBL21617679 | 0.66 | TXNRD1 (0.58) | JAK2TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877381-A1 | BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Lynk Pharmaceuticals Co. Ltd. (CN) | 2021-09-15 | — | — | EP | disclosed |
| WO-2020119819-A1 | BENZAMIDES OF PYRAZOLYL-AMINO-PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2020-06-18 | — | — | WO | disclosed |