SCHEMBL2890048

SCHEMBL2890048

CCCN(Cc1ccc(Cl)nc1)C1=CC(=O)CCC1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MT-CO2 P00403 1/20 0.36
ALDH1A1 P00352 2/20 0.35
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890160 0.90 MT-CO2 (0.37) MT-CO2ALDH1A1MEN1KMT2A
SCHEMBL2892730 0.83 MT-CO2 (0.39) MT-CO2ALDH1A1PSEN1PSEN2APH1B
SCHEMBL2893276 0.82 PSEN1 (0.33) MT-CO2ALDH1A1PSEN1PSEN2APH1B
SCHEMBL2891830 0.82 PSEN1 (0.35) MT-CO2ALDH1A1PSEN1PSEN2APH1B
SCHEMBL15182351 0.81 L3MBTL1 (0.35) ALDH1A1PSEN1PSEN2APH1BNCSTN
SCHEMBL15182350 0.75 ALDH1A1 (0.34) ALDH1A1PSEN1PSEN2APH1BNCSTN
SCHEMBL2893284 0.75 ALDH1A1 (0.42) ALDH1A1PSEN1PSEN2APH1BNCSTN
SCHEMBL9573718 0.70 MT-CO2 (0.47) MT-CO2ALDH1A1MEN1KMT2A
SCHEMBL2068336 0.69 HRH3 (0.49) ALDH1A1MEN1KMT2A
SCHEMBL2894001 0.69 PSEN1 (0.39) ALDH1A1PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US claimed
EP-2090168-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-08-19 EP claimed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP claimed
US-20130303376-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2013-11-14 US disclosed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100173943-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED ACTION BAYER CROPSCIENCE AG (DE) 2010-07-08 US disclosed
US-20100173943-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED ACTION BAYER CROPSCIENCE AG (DE) 2010-07-08 US disclosed
US-20100173943-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED ACTION BAYER CROPSCIENCE AG (DE) 2010-07-08 US disclosed
WO-2009118025-A1 METHOD FOR CONTROLLING ANIMAL PEST AND PLANT PATHOGENIC FUNGI BY APPLYING AN AGROCHEMICAL COMPOSITION INTO THE CULTURE MEDIUM, SUITABLE FORMULATION AND USE THEREOF BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-10-01 WO disclosed
WO-2009118027-A1 SUSPENSION CONCENTRATES FOR IMPROVING ROOT UPTAKE OF AGROCHEMICALLY ACTIVE COMPOUNDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-10-01 WO disclosed
WO-2009118025-A1 METHOD FOR CONTROLLING ANIMAL PEST AND PLANT PATHOGENIC FUNGI BY APPLYING AN AGROCHEMICAL COMPOSITION INTO THE CULTURE MEDIUM, SUITABLE FORMULATION AND USE THEREOF BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-10-01 WO disclosed
EP-2090168-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-08-19 EP disclosed
EP-2090168-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-08-19 EP disclosed
WO-2009046837-A2 METHODS OF IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2009-04-16 WO disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
EP-2044841-A1 Method for improving plant growth Bayer CropScience AG (DE) 2009-04-08 EP disclosed
WO-2008148483-A1 INSECTICIDE COMPOSITIONS HAVING AN IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2008-12-11 WO disclosed
EP-2000027-A1 Insecticide compounds with improved effect Bayer CropScience AG (DE) 2008-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285965-A1 METHODS OF IMPROVING PLANT GROWTH MYCBP, MYB, MRPL37 MT-CO2 379/4885ALDH1A1 4720/4885PSEN1 4114/4885
US-20100173943-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED ACTION PTEN, PHOSPHO1, ACHE MT-CO2 873/4885ALDH1A1 4848/4885PSEN1 477/4885
US-20130303376-A1 METHODS OF IMPROVING PLANT GROWTH MYCBP, MYB, MRPL37 MT-CO2 201/4885ALDH1A1 4767/4885PSEN1 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.