Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19950727 | 0.89 | NR1H2 (0.67) | KMT2AMEN1NR1H3POLBNR1H2 | |
| SCHEMBL29168849 | 0.84 | KMT2A (0.76) | KMT2AMEN1NR1H3NR1H2ALDH1A1 | |
| SCHEMBL30758650 | 0.84 | KMT2A (0.76) | KMT2AMEN1NR1H3NR1H2ALDH1A1 | |
| SCHEMBL4649466 | 0.82 | POLB (0.65) | KMT2AMEN1NR1H3POLBNR1H2 | |
| SCHEMBL11872977 | 0.80 | NPC1 (0.59) | KMT2AMEN1NR1H3POLBNR1H2 | |
| SCHEMBL2892688 | 0.79 | NR1H2 (0.49) | KMT2AMEN1NR1H3POLBNR1H2 | |
| SCHEMBL28450172 | 0.78 | MEN1 (0.51) | KMT2AMEN1NR1H3POLBNR1H2 | |
| SCHEMBL9806801 | 0.77 | LMNA (0.70) | KMT2AMEN1POLBNR1H2SMN1; SMN2 | |
| SCHEMBL9320871 | 0.77 | MGLL (0.71) | NR1H2ALDH1A1MGLL | |
| SCHEMBL10398325 | 0.75 | MGLL (0.69) | NR1H2ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660560-B1 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2016-03-23 | — | — | EP | disclosed |
| US-7714095-B2 | Phase transfer catalyzed method for preparation of polyetherimides | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2010-05-11 | — | — | US | disclosed |
| US-7605222-B2 | Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-10-20 | — | — | US | disclosed |
| EP-1660556-B1 | COPOLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-05-13 | — | — | EP | disclosed |
| EP-1989246-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES | Sabic Innovative Plastics IP B.V. (NL) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007100473-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETHERIMIDES | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2007-09-07 | — | — | WO | disclosed |
| US-20070043203-A1 | Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units | GENERAL ELECTRIC COMPANY (US) | 2007-02-22 | — | — | US | disclosed |
| US-20060173158-A1 | Phase transfer catalyzed method for preparation of polyetherimides | GENERAL ELECTRIC COMPANY (US) | 2006-08-03 | — | — | US | disclosed |
| EP-1660556-A1 | COPOLYETHERIMIDES | GENERAL ELECTRIC COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1660560-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | GENERAL ELECTRIC COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005023901-A1 | COPOLYETHERIMIDES | GENERAL ELECTRIC COMPANY (US) | 2005-03-17 | — | — | WO | disclosed |
| WO-2005021618-A2 | PHASE TRANSFER CATALYZED METHOD FOR PREPARATION OF POLYETEHRIMIDES | GENERAL ELECTRIC COMPANY (US) | 2005-03-10 | — | — | WO | disclosed |
| US-20050049390-A1 | Phase transfer catalyzed method for preparation of polyetherimides | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |
| US-6849706-B1 | Copolyetherimides | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173158-A1 | Phase transfer catalyzed method for preparation of polyetherimides | TRRAP, RCC1, DDT | KMT2A 326/4885MEN1 4568/4885NR1H3 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.