Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26761 | 0.88 | MEN1 (0.42) | CES1BCHEKDM4EALDH1A1HPGD | |
| SCHEMBL29530894 | 0.86 | MEN1 (0.41) | CES1BCHEKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7597249 | 0.86 | MEN1 (0.41) | CES1BCHEKDM4EALDH1A1HPGD | |
| Sulfuric Acid SCHEMBL3680446 | 0.81 | MEN1 (0.37) | CES1BCHEKDM4EALDH1A1HPGD | |
| SCHEMBL3273520 | 0.81 | MEN1 (0.37) | CES1BCHEKDM4EALDH1A1HPGD | |
| SCHEMBL4895477 | 0.81 | MEN1 (0.37) | CES1BCHEKDM4EALDH1A1HPGD | |
| Phenol SCHEMBL28798223 | 0.79 | APAF1 (0.38) | CES1BCHEKDM4EALDH1A1HPGD | |
| SCHEMBL5698405 | 0.79 | MEN1 (0.34) | CES1BCHEKDM4EALDH1A1MAOA | |
| Benzophenone SCHEMBL28692346 | 0.76 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL88188 | 0.75 | CES1 (0.52) | CES1BCHEKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108987-B | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2023-05-26 | — | — | CN | claimed |
| CN-115108987-A | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2022-09-27 | — | — | CN | claimed |
| CN-115108987-B | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115108987-A | N-substituted indenoisoquinolinone derivative and preparation method thereof | 华侨大学 | 2022-09-27 | — | — | CN | disclosed |