Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906179 | 0.77 | MAPT (0.45) | ALDH1A1MAPTNPSR1LMNAHTT | |
| SCHEMBL29940494 | 0.77 | MAPT (0.45) | ALDH1A1MAPTNPSR1LMNAHTT | |
| SCHEMBL28906152 | 0.75 | MEN1 (0.51) | ALDH1A1MAPTNPSR1LMNAMAOB | |
| SCHEMBL28906155 | 0.75 | PRNP (0.52) | ALDH1A1MAPTNPSR1LMNAHTT | |
| SCHEMBL11293660 | 0.69 | XDH (0.50) | ALDH1A1MAPTHPGDCYP3A4SMN1; SMN2 | |
| SCHEMBL6994467 | 0.69 | CA12 (0.46) | ALDH1A1MAPTNPSR1FAAHMGLL | |
| SCHEMBL8242977 | 0.67 | FAAH (0.54) | MAPTNPSR1FAAHMGLLLMNA | |
| SCHEMBL462156 | 0.66 | FAAH (0.56) | MAPTNPSR1FAAHMGLLLMNA | |
| SCHEMBL20072394 | 0.66 | CYP1A2 (0.41) | MAPTFAAHMGLLLMNAMAOB | |
| SCHEMBL5713066 | 0.65 | MAOA (0.47) | ALDH1A1MAPTMAOBHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |