Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940494 | 1.00 | MAPT (0.45) | MAPTATMELANEALDH1A1HTT | |
| SCHEMBL28906152 | 0.81 | MEN1 (0.51) | MAPTALDH1A1LMNAMAOBCYP2C9 | |
| SCHEMBL28906148 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1HTTTDP1LMNA | |
| SCHEMBL28906155 | 0.72 | PRNP (0.52) | MAPTELANEALDH1A1HTTTDP1 | |
| SCHEMBL29940885 | 0.70 | EPHX2 (0.57) | MAPTATMELANEALDH1A1HTT | |
| SCHEMBL28906138 | 0.70 | EPHX2 (0.57) | MAPTATMELANEALDH1A1HTT | |
| SCHEMBL16927398 | 0.67 | NR4A2 (0.46) | MAPTATMALDH1A1LMNACA12 | |
| SCHEMBL6439681 | 0.66 | MAOA (0.48) | MAPTALDH1A1LMNAMAOBCA12 | |
| SCHEMBL28906146 | 0.66 | KDM4E (0.48) | MAPTALDH1A1LMNAMAOBCA12 | |
| SCHEMBL29940757 | 0.66 | KDM4E (0.48) | MAPTALDH1A1LMNAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |