Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 6/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906152 | 0.81 | MEN1 (0.51) | RXFP1NPSR1MAPTPOLBCYP1A2 | |
| SCHEMBL28906148 | 0.75 | ALDH1A1 (0.46) | NPSR1MAPTL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL23119878 | 0.73 | SMN1; SMN2 (0.56) | NPSR1MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL28906179 | 0.72 | MAPT (0.45) | RXFP1NPSR1TSHRMAPTELANE | |
| SCHEMBL29940494 | 0.72 | MAPT (0.45) | RXFP1NPSR1TSHRMAPTELANE | |
| SCHEMBL2027600 | 0.70 | LMNA (0.59) | PRNPRXFP1NPSR1TSHRMAPT | |
| SCHEMBL11792108 | 0.70 | ALDH1A1 (0.56) | PRNPRXFP1NPSR1ALDH1A1HPGD | |
| SCHEMBL1572943 | 0.70 | KDM4E (0.52) | TSHRL3MBTL1POLBELANEALDH1A1 | |
| SCHEMBL30174438 | 0.70 | KDM4E (0.52) | TSHRL3MBTL1POLBELANEALDH1A1 | |
| Xanthone SCHEMBL27310536 | 0.70 | RAB9A (0.61) | MAPTALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |