Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906191 | 0.85 | LMNA (0.41) | IKBKEAKR1C3L3MBTL1KMT2AMEN1 | |
| SCHEMBL26097267 | 0.75 | CYP1A2 (0.35) | IKBKEAGBL2ALDH1A1KDM4ELMNA | |
| SCHEMBL24867893 | 0.73 | MAPK14 (0.38) | — | |
| SCHEMBL28906199 | 0.70 | LMNA (0.38) | AKR1C3KMT2AMEN1ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL30455778 | 0.69 | LDHA (0.34) | IKBKEAKR1C3KMT2AMEN1GPBAR1 | |
| SCHEMBL16708689 | 0.67 | POLB (0.45) | KMT2AMEN1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23363075 | 0.67 | L3MBTL1 (0.38) | L3MBTL1KMT2AMEN1GPBAR1SMN1; SMN2 | |
| SCHEMBL25224521 | 0.66 | LDHA (0.35) | KMT2AMEN1HDAC4POLBHCAR3 | |
| SCHEMBL23363199 | 0.66 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1KDM4EKDM2B | |
| SCHEMBL21590723 | 0.66 | NPC1 (0.45) | KMT2AMEN1AGBL2GPBAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | disclosed |