Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | KIF11 | P52732 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906353 | 0.81 | HTR2A (0.61) | HTR2AHTR2CDRD2TUBB4ATUBB | |
| SCHEMBL28906516 | 0.81 | HTR2A (0.62) | HTR2AHTR2CDRD2TUBB4ATUBB | |
| SCHEMBL27549075 | 0.79 | KIF11 (0.51) | KIF11MGAMGAASIMGAM2 | |
| SCHEMBL5635637 | 0.78 | KIF11 (0.47) | KIF11MGAMGAASIMGAM2 | |
| SCHEMBL28906369 | 0.78 | MAPT (0.55) | HTR2AHTR2CDRD2TUBB4ATUBB | |
| SCHEMBL28906371 | 0.78 | HTR2A (0.61) | HTR2AHTR2CDRD2TUBB4ATUBB | |
| SCHEMBL28906377 | 0.78 | PTGS2 (0.49) | HTR2AHTR2CDRD2TUBB4ATUBB | |
| SCHEMBL28906514 | 0.74 | KDM4E (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10443772 | 0.74 | TUBB4A (0.64) | HTR2AHTR2CKIF11DRD2TUBB4A | |
| SCHEMBL607944 | 0.72 | KIF11 (0.75) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304533-B | Bisindolemethane type alpha-glucosidase inhibitor and preparation method and application thereof | 中国医学科学院药用植物研究所云南分所 | 2024-04-12 | — | — | CN | disclosed |
| CN-117567447-A | Thiophene-containing bis-indolomethane type a-glucosidase inhibitor and preparation method and application thereof | 中国医学科学院药用植物研究所云南分所 | 2024-02-20 | — | — | CN | disclosed |
| CN-115304533-A | Bis-indole methane type alpha-glucosidase inhibitor and preparation method and application thereof | 中国医学科学院药用植物研究所云南分所 | 2022-11-08 | — | — | CN | disclosed |