Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.80 |
| ▸ | MAOB | P27338 | 10/20 | 0.80 |
| ▸ | FLT3 | P36888 | 2/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | FER | P16591 | 1/20 | 0.55 |
| ▸ | LTK | P29376 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP2 | P42575 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1897547 | 0.98 | MAOA (0.83) | MAOAMAOBFLT3LRRK2PDGFRA | |
| Isatin SCHEMBL28636865 | 0.96 | MAOA (0.80) | MAOAMAOBFLT3LRRK2PDGFRA | |
| Isatin SCHEMBL28365971 | 0.92 | MAOA (0.95) | MAOAMAOBFLT3LRRK2PDGFRA | |
| Tannin Pyrogallol SCHEMBL29283471 | 0.91 | MAOA (0.67) | MAOAMAOBFLT3LRRK2PDGFRA | |
| Isatin SCHEMBL28299080 | 0.91 | MAOA (0.72) | MAOAMAOBFLT3LRRK2PDGFRA | |
| Isatin SCHEMBL34016 | 0.89 | MAOA (1.00) | MAOAMAOBLRRK2PDGFRAFER | |
| Isatin SCHEMBL973760 | 0.89 | MAOA (1.00) | MAOAMAOBLRRK2PDGFRAFER | |
| Isatin SCHEMBL23256320 | 0.87 | MAOA (0.95) | MAOAMAOBLRRK2PDGFRAFER | |
| Isatin SCHEMBL1590864 | 0.87 | MAOA (0.95) | MAOAMAOBLRRK2PDGFRAFER | |
| Isatin SCHEMBL7061560 | 0.87 | MAOA (0.95) | MAOAMAOBLRRK2PDGFRAFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880138-B | High-performance polyisatin arene with long side chain ammonium salt, anion exchange membrane thereof, preparation method and application | 大连理工大学 | 2020-09-29 | — | — | CN | disclosed |