SCHEMBL289089

SCHEMBL289089

NCC1(C(=O)O)CCCCC1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.45
FABP7 O15540 2/20 0.45
KMT2A Q03164 2/20 0.43
EPHX2 P34913 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CASP3 P42574 2/20 0.35
HTR2A P28223 1/20 0.33
MAPK1 P28482 1/20 0.33
OPRD1 P41143 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524690 0.86 FABP5 (0.48) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL7401416 0.85 FABP5 (0.47) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL525363 0.82 FABP5 (0.49) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL28126888 0.80 FKBP1A (0.43) FABP5FABP7
SCHEMBL17699252 0.79 FABP5 (0.50) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL4789393 0.77 LMNA (0.41)
SCHEMBL12987541 0.76 FABP5 (0.44) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL12987564 0.76 FABP5 (0.44) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL4601031 0.75 FABP5 (0.45) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL12987567 0.75 KMT2A (0.42) FABP5FABP7KMT2AEPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254092-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES ACTINIUM PHARMACEUTICALS, INC. (US) 2024-08-01 US disclosed
US-11975081-B2 Bifunctional chelators and conjugates ACTINIUM PHARMACEUTICALS, INC. (US) 2024-05-07 US disclosed
US-11964948-B2 Bifunctional chelators and conjugates ACTINIUM PHARMACEUTICALS, INC. (US) 2024-04-23 US disclosed
US-20240082438-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES ACTINIUM PHARMACEUTICALS, INC. (US) 2024-03-14 US disclosed
US-20240051928-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES ACTINIUM PHARMACEUTICALS, INC. (US) 2024-02-15 US disclosed
EP-2427451-B1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CO LTD (JP) 2019-03-20 EP disclosed
US-20180305373-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO Prism BioLab Co., Ltd. (JP) 2018-10-25 US disclosed
US-10017522-B2 Alpha helix mimetics and methods relating thereto Prism BioLab Co., Ltd. (JP) 2018-07-10 US disclosed
US-20150368262-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO Prism BioLab Co., Ltd. (JP) 2015-12-24 US disclosed
US-9040531-B2 Alpha helix mimetics and methods relating thereto Prism BioLab Co., Ltd. (JP) 2015-05-26 US disclosed
US-20120088770-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CORPORATION (JP) 2012-04-12 US disclosed
EP-2427451-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BioLab Corporation (JP) 2012-03-14 EP disclosed
WO-2010128685-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CORPORATION (JP) 2010-11-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368262-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PLOD3, COL1A1, THPO FABP5 1359/4885FABP7 697/4885KMT2A 3392/4885
US-20120088770-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PLOD3, COL1A1, THPO FABP5 1359/4885FABP7 697/4885KMT2A 3392/4885
US-20240254092-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES FOLH1, PAICS, TAP2 FABP5 2172/4885FABP7 1451/4885KMT2A 1003/4885
US-11964948-B2 Bifunctional chelators and conjugates FOLH1, PAICS, TAP2 FABP5 2172/4885FABP7 1451/4885KMT2A 1003/4885
US-20240051928-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES FOLH1, PAICS, TAP2 FABP5 2172/4885FABP7 1451/4885KMT2A 1003/4885
US-20180305373-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PLOD3, COL1A1, THPO FABP5 1359/4885FABP7 697/4885KMT2A 3392/4885
US-11975081-B2 Bifunctional chelators and conjugates FOLH1, PAICS, TAP2 FABP5 2172/4885FABP7 1451/4885KMT2A 1003/4885
US-10017522-B2 Alpha helix mimetics and methods relating thereto PLOD3, COL1A1, THPO FABP5 1359/4885FABP7 697/4885KMT2A 3392/4885
US-20240082438-A1 BIFUNCTIONAL CHELATORS AND CONJUGATES FOLH1, PAICS, TAP2 FABP5 2172/4885FABP7 1451/4885KMT2A 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.