SCHEMBL2890901

SCHEMBL2890901

CCCCCC(CC)OC(=O)C(O)C(O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.46
FFAR1 O14842 2/20 0.46
MAPT P10636 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
PRKCA P17252 1/20 0.39
PRKCD Q05655 1/20 0.39
CA2 P00918 1/20 0.39
MAPK1 P28482 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890897 0.93 PRKCA (0.43) GPR84FFAR1PRKCAPRKCDCA2
SCHEMBL17986644 0.92 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL3205518 0.88 PRKCA (0.41) GPR84FFAR1PRKCAPRKCDCA2
SCHEMBL2230260 0.85 CTSK (0.43) GPR84FFAR1MAPTLCKPPARD
SCHEMBL17986643 0.84 GPR84 (0.48) GPR84FFAR1MAPTLCKPPARD
SCHEMBL10797828 0.83 GPR84 (0.48) GPR84FFAR1MAPTLCKPPARD
SCHEMBL29704031 0.81 GPR84 (0.47) GPR84FFAR1MAPTLCKPPARD
SCHEMBL16180420 0.81 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL28687233 0.81 GPR84 (0.46) GPR84FFAR1PRKCAPRKCDCA2
SCHEMBL29682914 0.81 CA1 (0.46) GPR84FFAR1MAPTPRKCAPRKCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286007-A1 Tartaric Acid Derivatives as Fuel Economy Improvers and Antiwear Agents in Crankcase Oils and Preparation Thereof THE LUBRIZOL CORPORATION (US) 2010-11-11 US disclosed
EP-2089496-A1 TARTARIC ACID DERIVATIVES AS FUEL ECONOMY IMPROVERS AND ANTIWEAR AGENTS IN CRANKCASE OILS AND PREPARATION THEREOF The Lubrizol Corporation (US) 2009-08-19 EP disclosed
WO-2008067259-A1 TARTARIC ACID DERIVATIVES AS FUEL ECONOMY IMPROVERS AND ANTIWEAR AGENTS IN CRANKCASE OILS AND PREPARATION THEREOF THE LUBRIZOL CORPORATION (US) 2008-06-05 WO disclosed