SCHEMBL3205518

SCHEMBL3205518

CCCC(CC)OC(=O)C(O)C(O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.41
PRKCD Q05655 2/20 0.41
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 1/20 0.37
CA2 P00918 2/20 0.34
MAPK1 P28482 1/20 0.34
GPR84 Q9NQS5 3/20 0.33
FFAR1 O14842 1/20 0.33
CTSK P43235 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2890901 0.88 GPR84 (0.46) PRKCAPRKCDCA2MAPK1GPR84
SCHEMBL2230260 0.86 CTSK (0.43) PRKCAPRKCDCHRM1AKR1A1CHRM3
SCHEMBL536311 0.84 HDAC1 (0.35) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL2890897 0.79 PRKCA (0.43) PRKCAPRKCDCA2GPR84FFAR1
SCHEMBL17986644 0.79 GPR84 (0.52) GPR84FFAR1GRIK1GRIK2
SCHEMBL25275003 0.79 PRKCA (0.44) PRKCAPRKCDCHRM1AKR1A1CHRM3
SCHEMBL29924052 0.79 PRKCA (0.44) PRKCAPRKCDCHRM1AKR1A1CHRM3
SCHEMBL793155 0.79 TSHR (0.42) TSHR
SCHEMBL4840489 0.79 PRKCA (0.44) PRKCAPRKCDCHRM1AKR1A1CHRM3
SCHEMBL2231280 0.76 PRKCA (0.40) PRKCAPRKCDCHRM1AKR1A1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES BROADLEY KENNETH N 2010-02-11 US disclosed
US-20100029978-A1 RAPIDLY CURING CYANOACRYLATES AS ADHESIVES SWORDS NOELEEN 2010-02-04 US disclosed
US-20060241226-A1 GAP-FILLING CYANOACRYLATE ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-10-26 US disclosed
US-6617385-B1 Alkylene biscyanoacrylate; addition polymer; ester plasticizer HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035997-A1 KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES KIT, TEKT1, CUTA PRKCA 33/4885PRKCD 85/4885CHRM1 3023/4885
US-20100029978-A1 RAPIDLY CURING CYANOACRYLATES AS ADHESIVES ICAM1, ITGA1, ITGA5 PRKCA 1495/4885PRKCD 2960/4885CHRM1 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.