Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986644 | 0.90 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL3205518 | 0.86 | PRKCA (0.41) | CTSKCA2MAPK1GPR84FFAR1 | |
| SCHEMBL536311 | 0.85 | HDAC1 (0.35) | CTSKGPR84FFAR1CHRM1AKR1A1 | |
| SCHEMBL2890901 | 0.85 | GPR84 (0.46) | CA2MAPK1GPR84FFAR1MAPT | |
| SCHEMBL17986643 | 0.82 | GPR84 (0.48) | MAPK1GPR84FFAR1MAPTLCK | |
| SCHEMBL15821165 | 0.80 | CTSK (0.46) | CTSKCA2CA1ACHEBACE1 | |
| SCHEMBL28164462 | 0.79 | CTSK (0.45) | CTSKCA2MAPK1GPR84CA1 | |
| SCHEMBL28184365 | 0.78 | CTSK (0.47) | CTSKCA2MAPK1CA1TDP1 | |
| SCHEMBL1242013 | 0.78 | GPR84 (0.43) | CTSKCA2MAPK1GPR84FFAR1 | |
| SCHEMBL1836821 | 0.77 | CTSK (0.50) | CTSKCA2MAPK1GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151102-A | POLYISOBUTYLENE, ESTER OF ALPHA-HYDROXY ACID, UNSATURATED ACID | SWISS ALUMINIUM LTD. (CH) | 1979-04-24 | — | — | US | claimed |
| US-9919993-B2 | Process for preparation of acitrecin | EMCURE PHARMACEUTICALS LIMITED (IN) | 2018-03-20 | — | — | US | disclosed |
| US-20170275229-A1 | PROCESS FOR PREPARATION OF ACITRECIN | EMCURE PHARMACEUTICALS LIMITED (IN) | 2017-09-28 | — | — | US | disclosed |
| CN-107207456-A | Latent acid and application thereof | 巴斯夫欧洲公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2016042573-A1 | PROCESS FOR PREPARATION OF ACITRETIN | EMCURE PHARMACEUTICALS LIMITED (IN) | 2016-03-24 | — | — | WO | disclosed |
| CN-104846665-A | Improved woven fabric pigment | HUZHOU SHENGHANG TEXTILE CO LTD | 2015-08-19 | — | — | CN | disclosed |
| CN-104010825-A | Irreversible thermochromic ink compositions | SANFORD LP | 2014-08-27 | — | — | CN | disclosed |
| CN-103221032-A | Pharmaceutical composition | CIPLA LTD | 2013-07-24 | — | — | CN | disclosed |
| US-8174648-B2 | Cellulose acylate film, process for producing the same, and polarizing plate and liquid crystal display device having the same | FUJIFILM CORPORATION (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20110181812-A1 | CELLULOSE ACYLATE FILM, PROCESS FOR PRODUCING THE SAME, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE HAVING THE SAME | FUJIFILM CORPORATION (JP) | 2011-07-28 | — | — | US | disclosed |
| CN-101156855-A | Modified release compositions containing short-acting hypnotics for the treatment of sleep disorders | ELAN PHARM INC (US) | 2008-04-09 | — | — | CN | disclosed |
| CN-1738608-A | Modified release compositions containing short-acting hypnotics for the treatment of sleep disorders | ELAN PHARM INC (US) | 2006-02-22 | — | — | CN | disclosed |
| US-6894144-B1 | Two-constituent elastomer materials based on alkyl aziridine comprising a catalyst constituent that contains a boric acid complex | 3M ESPE AG (DE) | 2005-05-17 | — | — | US | disclosed |
| US-4151102-A | POLYISOBUTYLENE, ESTER OF ALPHA-HYDROXY ACID, UNSATURATED ACID | SWISS ALUMINIUM LTD. (CH) | 1979-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275229-A1 | PROCESS FOR PREPARATION OF ACITRECIN | PTMA, MC5R, MC4R | CTSK 3742/4885CA2 1120/4885MAPK1 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.