Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31075128 | 0.85 | ALDH1A1 (0.32) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30381152 | 0.84 | RAB9A (0.40) | RAB9ANPC1PKMMAPTKDM4E | |
| SCHEMBL29714449 | 0.84 | NPC1 (0.35) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL38665543 | 0.84 | RAB9A (0.40) | RAB9ANPC1PKMMAPTKDM4E | |
| SCHEMBL29387123 | 0.84 | MAPT (0.34) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL28831144 | 0.82 | NPC1 (0.35) | RAB9ANPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL26123782 | 0.82 | RAB9A (0.40) | RAB9ANPC1PKMMAPTKDM4E | |
| SCHEMBL3485726 | 0.79 | FABP5 (0.41) | RAB9ANPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL8229967 | 0.78 | RAB9A (0.35) | RAB9ANPC1PKMPNMTMAPT | |
| SCHEMBL28918336 | 0.77 | PNMT (0.43) | RAB9ANPC1PNMTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748183-B1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIV LEIPZIG (DE) | 2018-12-26 | — | — | EP | disclosed |
| US-9718861-B2 | Potent ligands of the ghrelin receptor | UNIVERSITAET LEIPZIG (DE) | 2017-08-01 | — | — | US | disclosed |
| US-20150274781-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITAET LEIPZIG (DE) | 2015-10-01 | — | — | US | disclosed |
| EP-2748183-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | Universität Leipzig (DE) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026927-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITÄT LEIPZIG (DE) | 2013-02-28 | — | — | WO | disclosed |
| EP-2562181-A1 | Potent ligands of the ghrelin receptor | Universität Leipzig (DE) | 2013-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274781-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | GIPR, GPR119, GRPR | RAB9A 1277/4885NPC1 1650/4885PKM 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.