Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | TET3 | O43151 | 2/20 | 0.35 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.35 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.35 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249699 | 0.73 | ELOVL1 (0.44) | KMT2AMEN1SLC6A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL28487473 | 0.73 | SLC6A4 (0.46) | KMT2AMEN1SLC6A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL31560810 | 0.73 | ELOVL1 (0.44) | KMT2AMEN1SLC6A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL28426673 | 0.71 | AKR1C1 (0.53) | KMT2AMEN1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6553149 | 0.68 | SLC6A4 (0.46) | KMT2AMEN1SLC6A4LMNASLC6A2 | |
| SCHEMBL11048173 | 0.68 | SLC6A4 (0.46) | KMT2AMEN1SLC6A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL16833940 | 0.67 | SLC6A4 (0.44) | KMT2AMEN1SLC6A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL7602755 | 0.65 | AKR1C1 (0.50) | KMT2AMEN1SLC6A4SMN1; SMN2L3MBTL1 | |
| SCHEMBL28149790 | 0.64 | AKR1C1 (0.46) | KMT2AMEN1SLC6A4POLBGAA | |
| SCHEMBL29642400 | 0.63 | PNMT (0.42) | KMT2AMEN1L3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536573-B | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115536573-A | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2022-12-30 | — | — | CN | disclosed |