Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11048158 | 0.86 | SLC6A4 (0.44) | SLC6A4OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL28487473 | 0.82 | SLC6A4 (0.46) | SLC6A4OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11045957 | 0.76 | OPRM1 (0.49) | SLC6A4OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL31560810 | 0.74 | ELOVL1 (0.44) | SLC6A4MEN1KMT2APOLBMAPT | |
| SCHEMBL20249699 | 0.74 | ELOVL1 (0.44) | SLC6A4MEN1KMT2APOLBMAPT | |
| SCHEMBL6553149 | 0.72 | SLC6A4 (0.46) | SLC6A4OPRM1MEN1KMT2APOLB | |
| SCHEMBL28149790 | 0.72 | AKR1C1 (0.46) | SLC6A4MEN1KMT2APOLBGAA | |
| SCHEMBL28426673 | 0.72 | AKR1C1 (0.53) | MEN1KMT2AHTTNPSR1SMN1; SMN2 | |
| SCHEMBL28922129 | 0.68 | KMT2A (0.37) | SLC6A4MEN1KMT2APOLBGAA | |
| SCHEMBL16833940 | 0.68 | SLC6A4 (0.44) | SLC6A4MEN1KMT2APOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478836-A | 1-Aryl 2-aminomethyl cyclopropane carboxyamide (Z) derivatives and their use as useful drugs in the treatment of disturbances of the central nervous system | PIERRE FABRE S.A. (FR) | 1984-10-23 | — | — | US | disclosed |