SCHEMBL28923

SCHEMBL28923

O=[C]OCc1ccccc1Br

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.55
ALDH1A1 P00352 3/20 0.45
PARP10 Q53GL7 1/20 0.44
TAAR1 Q96RJ0 3/20 0.42
FFAR4 Q5NUL3 2/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP12 P39900 1/20 0.41
FFAR1 O14842 1/20 0.41
MAPT P10636 4/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39
KMT2A Q03164 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11110722 0.84 GABRA1 (0.39) IDO1ALDH1A1PARP10TAAR1MMP1
SCHEMBL5546594 0.80 TAAR1 (0.48) IDO1ALDH1A1PARP10TAAR1FFAR4
SCHEMBL5984175 0.77 GABRA1 (0.41) IDO1MAPT
SCHEMBL6602034 0.76 PYCR1 (0.40) IDO1ALDH1A1MAPTRAB9ANPC1
SCHEMBL1937871 0.75 IDO1 (0.55) IDO1TAAR1
SCHEMBL98917 0.75 IDO1 (0.55) IDO1TAAR1MMP1MMP2MMP9
SCHEMBL177343 0.75 FDPS (0.38) IDO1ALDH1A1SMN1; SMN2POLB
SCHEMBL5519683 0.75 IDO1 (0.55) IDO1TAAR1CA12CA9TSHR
SCHEMBL98042 0.75 IDO1 (0.55) IDO1ALDH1A1PARP10TAAR1MMP1
SCHEMBL133171 0.75 MAOB (0.45) ALDH1A1TAAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6337 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779653-B2 Multi-armed polyrotaxane platform for protected nucleic acid delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-10 US claimed
EP-3565573-B1 PAC1 RECEPTOR AGONISTS (MAXCAPS) AND USES THEREOF UNIV CALIFORNIA (US) 2023-08-23 EP claimed
US-11713340-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-08-01 US claimed
US-11673957-B2 Anti-ROR2 antibodies Eureka Therapeutics, Inc. (US) 2023-06-13 US claimed
US-11603369-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-03-14 US claimed
US-11555055-B2 Peptide inhibitors of insulin-degrading enzyme THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-01-17 US claimed
CN-114907272-A Bivalent nucleobase compound and use thereof 卡耐基梅隆大学 2022-08-16 CN claimed
US-20220175872-A1 THERMOGENIC COMPOSITIONS AND METHODS OHIO STATE INNOVATION FOUNDATION 2022-06-09 US claimed
US-20200376139-A1 MULTI-ARMED POLYROTAXANE PLATFORM FOR PROTECTED NUCLEIC ACID DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-12-03 US claimed
US-20200354407-A1 PEPTIDE INHIBITORS OF INSULIN-DEGRADING ENZYME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-11-12 US claimed
US-4055524-A RESIN PEPTIDE ARMOUR PHARMACEUTICAL COMPANY (US) 1977-10-25 US claimed
US-4024121-A (Pyro)-Glu-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHR and intermediates SCHALLY ANDREW VICTOR 1977-05-17 US claimed
US-4018726-A [D-Phe6 ]-LH-RH and intermediates therefor SCHALLY ANDREW VICTOR 1977-04-19 US claimed
US-4012345-A POLYPEPTIDES WHICH INHIBIT SECRETION OF GROWTH HORMONE SOMATOTROPIN AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-15 US claimed
US-4010125-A [D-Trp6 ]-LH-RH and intermediates therefor SCHALLY ANDREW VICTOR 1977-03-01 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3998795-A (Acyl-D-α-amino acid-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-21 US claimed
US-3997517-A PEPTIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-14 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed