Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.88 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3797065 | 1.00 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| Potassium Ion SCHEMBL28710581 | 1.00 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| Potassium Ion SCHEMBL15387897 | 1.00 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| Potassium Ion SCHEMBL15300393 | 1.00 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| Potassium Ion SCHEMBL18317043 | 0.98 | CA2 (0.92) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| Potassium Ion SCHEMBL31730243 | 0.98 | CA2 (0.92) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL5704847 | 0.95 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL6280096 | 0.95 | CA2 (0.88) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL15387890 | 0.95 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 | |
| SCHEMBL4254221 | 0.95 | CA2 (0.96) | CA2NFKB1CYP3A4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115400385-A | Water-soluble fire extinguishing tablet, preparation method thereof and fire extinguishing water agent | 清华大学 | 2022-11-29 | — | — | CN | disclosed |