Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795983 | 0.84 | KDM4E (0.38) | MEN1KMT2APOLBSMN1; SMN2KDM4E | |
| SCHEMBL25120101 | 0.84 | KDM4E (0.34) | MEN1KMT2ACHEK1GLAPOLB | |
| SCHEMBL29238904 | 0.79 | MBOAT4 (0.34) | — | |
| SCHEMBL3098852 | 0.79 | CTSK (0.34) | MEN1KMT2AHPGDKDM4EMAPT | |
| SCHEMBL26690256 | 0.79 | RECQL (0.43) | HPGDSMN1; SMN2KDM4EGAAMAPT | |
| SCHEMBL3080824 | 0.79 | GABRA1 (0.36) | — | |
| SCHEMBL31039307 | 0.79 | NT5E (0.38) | HPGDGPR35KDM4EGAA | |
| SCHEMBL3101735 | 0.79 | NT5E (0.38) | HPGDGPR35KDM4EGAA | |
| SCHEMBL28675605 | 0.76 | SMN1; SMN2 (0.58) | MEN1KMT2AGLAPOLBHPGD | |
| SCHEMBL16125570 | 0.74 | RAD51 (0.37) | MEN1KMT2AGLAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403562-A | 2',6' -di-2- (1-hydrogen imidazolyl) -4-halogenated pyridine compound and preparation method and application thereof | 深圳大学 | 2022-11-29 | — | — | CN | claimed |
| CN-115403562-A | 2',6' -di-2- (1-hydrogen imidazolyl) -4-halogenated pyridine compound and preparation method and application thereof | 深圳大学 | 2022-11-29 | — | — | CN | disclosed |