Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928859 | 0.83 | POLB (0.52) | KDM4ELMNAALDH1A1HDAC1HDAC10 | |
| SCHEMBL27855054 | 0.82 | HDAC3 (0.48) | CYP1A2CYP2D6KDM4ELMNAHDAC1 | |
| SCHEMBL28928823 | 0.82 | LMNA (0.65) | KDM4ELMNAALDH1A1MAPTHDAC1 | |
| SCHEMBL28928830 | 0.82 | MEN1 (0.64) | KDM4ELMNAALDH1A1MAPTHDAC1 | |
| SCHEMBL28929418 | 0.81 | NPC1 (0.59) | CYP1A2CYP2D6KDM4EHPGDALDH1A1 | |
| SCHEMBL28928863 | 0.78 | DAO (0.49) | KDM4EHPGDALDH1A1MAPTHDAC1 | |
| SCHEMBL28928832 | 0.77 | NPC1 (0.45) | KDM4ELMNAMAPTHDAC1HDAC10 | |
| SCHEMBL28928827 | 0.76 | CYP1A2 (0.46) | CYP1A2CYP2D6KDM4ELMNAALDH1A1 | |
| SCHEMBL23014396 | 0.76 | ALDH1A1 (0.54) | KDM4ELMNAHPGDALDH1A1MAPT | |
| SCHEMBL12634168 | 0.76 | ALDH1A1 (0.52) | KDM4EALDH1A1HDAC1HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |