Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 9/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28932570 | 0.81 | OXER1 (0.54) | DHFRTLR8OXER1TLR7 | |
| SCHEMBL30282852 | 0.80 | TLR8 (0.44) | TLR8PPARGPPARAOXER1TP53 | |
| SCHEMBL16452868 | 0.72 | CYP2A6 (0.41) | TP53KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL19329642 | 0.70 | TLR8 (0.39) | TLR8PPARGPPARAOXER1KDM4E | |
| SCHEMBL21907072 | 0.65 | HTR2A (0.39) | DHFRTLR8PPARGPPARARORC | |
| SCHEMBL16452837 | 0.64 | MAPT (0.50) | DHFRTP53MEN1KMT2A | |
| SCHEMBL1648335 | 0.64 | CYP2A6 (0.50) | TP53KDM4EALDH1A1 | |
| SCHEMBL1315631 | 0.64 | HTR2A (0.42) | TLR8OXER1TP53RORARORC | |
| SCHEMBL28283584 | 0.64 | BRPF1 (0.46) | TLR8OXER1MEN1KMT2A | |
| SCHEMBL19135849 | 0.63 | DHFR (0.43) | DHFROXER1SLC2A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912529-B | Method for synthesizing indole compounds by catalyzing N-aryl amide compounds and vinylene carbonate with ruthenium | 成都大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113912529-A | Method for synthesizing indole compound by catalyzing N-aryl amide compound and vinylene carbonate with ruthenium | 成都大学 | 2022-01-11 | — | — | CN | disclosed |