Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426398 | 0.83 | MEN1 (0.55) | MEN1KMT2AMGLLSCN9ASCN10A | |
| SCHEMBL9819404 | 0.81 | MGLL (0.47) | MEN1KMT2AMGLLMAPTALDH1A1 | |
| SCHEMBL9819470 | 0.80 | ALDH1A1 (0.41) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9819442 | 0.79 | ADRA2C (0.44) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28933339 | 0.79 | KMT2A (0.61) | MEN1KMT2AMGLLMAPTEPHX2 | |
| SCHEMBL9819361 | 0.78 | POLB (0.49) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11428297 | 0.78 | OPRK1 (0.45) | MEN1KMT2AMGLLALDH1A1L3MBTL1 | |
| SCHEMBL6366715 | 0.76 | POLB (0.46) | MEN1KMT2AMGLLALDH1A1L3MBTL1 | |
| SCHEMBL9819320 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27936178 | 0.75 | KMT2A (0.57) | MEN1KMT2AMGLLEPHX2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162669-B1 | ANTICONVULSIVE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4588729-A | Treating convulsions with dihydrouracil derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| EP-0162669-A2 | Anticonvulsive compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |