Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559860 | 0.95 | RECQL (0.39) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL8562912 | 0.77 | HSD17B10 (0.32) | — | |
| SCHEMBL2099384 | 0.75 | — | — | |
| SCHEMBL300353 | 0.75 | — | — | |
| SCHEMBL7605884 | 0.73 | — | — | |
| SCHEMBL14954909 | 0.73 | — | — | |
| SCHEMBL28550812 | 0.73 | — | — | |
| Fluoride SCHEMBL27598849 | 0.73 | CA2 (0.30) | — | |
| SCHEMBL10823123 | 0.73 | RECQL (0.35) | RECQLGLAHPGDTSHRMAPK1 | |
| SCHEMBL8664706 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118165175-A | Temperature-sensitive macromonomer, anti-segregation high-adaptability polycarboxylate superplasticizer using same and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-114149650-A | Salt-resistant antibacterial super absorbent resin and preparation method thereof | 安徽富瑞雪化工科技股份有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-118165175-A | Temperature-sensitive macromonomer, anti-segregation high-adaptability polycarboxylate superplasticizer using same and preparation method thereof | 江苏苏博特新材料股份有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-110156944-B | Four-arm star-shaped block polycarboxylic acid superplasticizer and preparation method and application thereof | 中科广化（重庆）新材料研究院有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-114149650-A | Salt-resistant antibacterial super absorbent resin and preparation method thereof | 安徽富瑞雪化工科技股份有限公司 | 2022-03-08 | — | — | CN | disclosed |