Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 9/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143994 | 1.00 | DGAT1 (0.47) | DGAT1SMOCNR2RETLRRK2 | |
| SCHEMBL31144021 | 0.84 | RET (0.50) | DGAT1RETLRRK2 | |
| SCHEMBL28703231 | 0.80 | SYK (0.42) | DGAT1SMOCNR2RETKCNH2 | |
| SCHEMBL28703261 | 0.76 | PGK1 (0.54) | RET | |
| SCHEMBL28715860 | 0.74 | RET (0.52) | RETSYK | |
| SCHEMBL28936733 | 0.73 | HDAC1 (0.47) | RET | |
| SCHEMBL28715846 | 0.72 | SYK (0.44) | DGAT1CNR2RETKCNH2SYK | |
| SCHEMBL23093304 | 0.72 | PTGS2 (0.49) | SYK | |
| SCHEMBL31143999 | 0.72 | RET (0.41) | CNR2RETSYKPDE10A | |
| SCHEMBL28711627 | 0.72 | RET (0.41) | CNR2RETSYKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |