Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | PPME1 | Q9Y570 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28711241 | 0.84 | HTR6 (0.40) | CTSGCMA1PPME1HTR6CYP11B1 | |
| SCHEMBL28700640 | 0.80 | HTR6 (0.44) | HTR6 | |
| SCHEMBL28716232 | 0.80 | HTR6 (0.51) | HTR6 | |
| SCHEMBL28715521 | 0.80 | PKM (0.42) | HTR6FEN1AKR1C3 | |
| SCHEMBL28719532 | 0.77 | HTR6 (0.47) | HTR6 | |
| SCHEMBL28715560 | 0.77 | HTR6 (0.49) | CTSGCMA1HTR6 | |
| SCHEMBL28649362 | 0.73 | NAPRT (0.42) | HTR6CYP11B1CYP11B2 | |
| SCHEMBL28715559 | 0.71 | PKM (0.45) | HTR6 | |
| SCHEMBL8220526 | 0.70 | AKR1C3 (0.50) | CTSGCMA1CYP11B1CYP11B2AKR1C3 | |
| SCHEMBL31754845 | 0.70 | RORC (0.42) | PPME1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105962-A | Compound containing sulfonamide structure, preparation method and application thereof, and pharmaceutical composition and application thereof | 南京烁慧医药科技有限公司 | 2022-03-01 | — | — | CN | disclosed |