Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22234554 | 0.74 | ALOX5AP (0.37) | ALOX5APFEN1 | |
| SCHEMBL22834846 | 0.72 | MAPK1 (0.32) | POLBIRAK4 | |
| SCHEMBL29598013 | 0.69 | AAK1 (0.38) | — | |
| SCHEMBL22843009 | 0.69 | AAK1 (0.38) | — | |
| SCHEMBL20639934 | 0.65 | DGAT1 (0.40) | POLBPARP10 | |
| SCHEMBL31438497 | 0.64 | — | — | |
| SCHEMBL23803694 | 0.63 | SQOR (0.40) | POLBIRAK4CCNE1CDK2ALOX5AP | |
| SCHEMBL31535408 | 0.63 | ALDH1A1 (0.47) | IRAK4 | |
| SCHEMBL6990968 | 0.63 | CCNC (0.37) | POLB | |
| SCHEMBL15881230 | 0.62 | NNMT (0.46) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114245796-A | Imidazo [1,2-a ] pyridinyl derivatives and their use in the treatment of disease | 比奥根MA公司 | 2022-03-25 | — | — | CN | disclosed |