Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634081 | 0.82 | L3MBTL1 (0.44) | ADRA2AADRA2BADRA2CL3MBTL1PLAU | |
| SCHEMBL4634579 | 0.82 | LIPE (0.47) | L3MBTL1LIPEPTK2MAOBGRM8 | |
| SCHEMBL27379515 | 0.81 | PTK2 (0.49) | L3MBTL1LIPEPTK2GRM8GRM7 | |
| SCHEMBL29078226 | 0.78 | NNMT (0.42) | NNMTMAPT | |
| SCHEMBL22557500 | 0.78 | KDM4E (0.44) | ADRA2AADRA2BADRA2CNNMT | |
| SCHEMBL9572467 | 0.78 | KMT2A (0.45) | NNMTMAPT | |
| SCHEMBL8459579 | 0.78 | PTK2 (0.50) | L3MBTL1LIPEPTK2MAPT | |
| SCHEMBL2899777 | 0.77 | KDM4E (0.46) | ADRA2AADRA2BADRA2CPLAUNNMT | |
| SCHEMBL20639594 | 0.77 | NNMT (0.41) | L3MBTL1NNMTMAPT | |
| SCHEMBL28476110 | 0.77 | KDM4E (0.58) | ADRA2AADRA2BADRA2CPLAUNNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591212-A | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |