SCHEMBL289384

SCHEMBL289384

CC(C)(C)P(C(C)(C)C)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 3/20 0.35
GRIN3B O60391 3/20 0.35
GRIN1 Q05586 3/20 0.35
GRIN2A Q12879 3/20 0.35
GRIN2B Q13224 3/20 0.35
GRIN2C Q14957 3/20 0.35
GRIN3A Q8TCU5 3/20 0.35
SLC22A2 O15244 2/20 0.33
SLC47A1 Q96FL8 2/20 0.33
LMNA P02545 2/20 0.33
SLC22A1 O15245 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
STAT6 P42226 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
POLB P06746 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1577736 0.79 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3840062 0.75 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24542199 0.70 MEN1 (0.34)
SCHEMBL1092580 0.69 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2929198 0.69 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1877773 0.67 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3629491 0.63 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2919595 0.63 SLC22A2 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2926239 0.63 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2928546 0.63 SLC22A2 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427468-B2 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2025-06-04 EP claimed
US-20240116965-A1 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2024-04-11 US claimed
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 EP claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 WO claimed
EP-2427468-B1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2017-06-14 EP claimed
US-8772520-B2 Preparation of a metal complex JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2014-07-08 US claimed
US-20120116109-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-05-10 US claimed
EP-2427468-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2012-03-14 EP claimed
WO-2010128316-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-11-11 WO claimed
EP-3892611-B1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN IND LTD (JP) 2026-01-28 EP disclosed
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-07-03 US disclosed
EP-2427468-B2 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2025-06-04 EP disclosed
US-12281075-B2 Method for producing fluorovinyl amide compound DAIKIN INDUSTRIES, LTD. (JP) 2025-04-22 US disclosed
US-20240317779-A1 METAL COMPLEXES HAVING 4-H,6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF UMICORE AG & CO. KG (DE) 2024-09-26 US disclosed
US-20060020148-A1 Process for producing tertiary phosphine having bulky hydrocarbon group bonded HOLLO CHEMICAL INDUSTRY CO., LTD (JP) 2006-01-26 US disclosed
EP-1473297-A1 PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) 2004-11-03 EP disclosed
US-20040068131-A1 (adamantyl)nP(alkyl)m(1a); (adamantyl)o(Alkyl)qP (alkylene')P(adamantyl)r(alkyl)s , wherein adamantyl bonded to phosphorus atom in position 1, or 2, useful for refining halogenoaromatics EVONIK DEGUSSA GMBH (DE) 2004-04-08 US disclosed
EP-1303525-A1 PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS Degussa AG (DE) 2003-04-23 EP disclosed
WO-2002010178-A1 ADAMANTYL GROUPS CONTAINING PHOSPHANE LIGANDS, THE PRODUCTION AND USE THEREOF IN CATALYTICAL REACTIONS DEGUSSA AG (DE) 2002-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060020148-A1 Process for producing tertiary phosphine having bulky hydrocarbon group bonded HRH3, HRH4, HRH1 GRIN2D 2366/4885GRIN3B 1363/4885GRIN1 1757/4885
US-20040068131-A1 (adamantyl)nP(alkyl)m(1a); (adamantyl)o(Alkyl)qP (alkylene')P(adamantyl)r(alkyl)s , wherein adamantyl bonded to phosphorus atom in position 1, or 2, useful for refining halogenoaromatics NAPEPLD, NAPA, APBA1 GRIN2D 1630/4885GRIN3B 2849/4885GRIN1 1180/4885
US-12281075-B2 Method for producing fluorovinyl amide compound RB1, KRAS, NRAS GRIN2D 2392/4885GRIN3B 2453/4885GRIN1 1081/4885
US-20250214936-A1 METHOD FOR PRODUCING FLUOROVINYL AMIDE COMPOUND RB1, KRAS, NRAS GRIN2D 2392/4885GRIN3B 2453/4885GRIN1 1081/4885
US-20240116965-A1 ORGANOMETALLIC COMPOUNDS DDT, PPOX, PDCD2L GRIN2D 2384/4885GRIN3B 1642/4885GRIN1 2170/4885
US-20240317779-A1 METAL COMPLEXES HAVING 4-H,6-H OR 8-H DIHYDROAZULENYL LIGANDS AND USE THEREOF DOHH, CPNE4, MDH2 GRIN2D 838/4885GRIN3B 909/4885GRIN1 754/4885
US-20120116109-A1 PREPARATION OF A METAL COMPLEX PDCD1LG2, CD274, PDCD2L GRIN2D 2388/4885GRIN3B 1533/4885GRIN1 3192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.