SCHEMBL28939591

SCHEMBL28939591

O=CNc1ccc2c(c1)CCOC2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
P2RX3 P56373 1/20 0.34
MAPK1 P28482 1/20 0.33
MAP4K1 Q92918 1/20 0.32
BTK Q06187 1/20 0.32
HPGD P15428 3/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
PIR O00625 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
HTR6 P50406 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
OPRD1 P41143 2/20 0.30
PIK3CD O00329 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17361823 0.86 ALDH1A1 (0.39) ALDH1A1MAPK1HPGDNPC1RAB9A
SCHEMBL24783883 0.77 MAP4K1 (0.36) ALDH1A1P2RX3MAPK1MAP4K1BTK
SCHEMBL4808457 0.77 NPC1 (0.49) ALDH1A1HPGDHTTNPC1RAB9A
SCHEMBL6291312 0.75 NPC1 (0.45) ALDH1A1MAPK1HPGDALOX15HTT
SCHEMBL6628521 0.74 ALDH1A1 (0.42) ALDH1A1HPGDRAB9AHTR6SMN1; SMN2
SCHEMBL29935913 0.74 ALDH1A1 (0.42) ALDH1A1HPGDRAB9AHTR6SMN1; SMN2
SCHEMBL25124377 0.73 P2RX3 (0.38) ALDH1A1P2RX3MAPK1MAP4K1BTK
SCHEMBL6204464 0.72 MAPT (0.38) ALDH1A1P2RX3MAPK1HPGDALOX15
SCHEMBL21894537 0.70 BTK (0.38) ALDH1A1P2RX3MAPK1MAP4K1BTK
SCHEMBL7802493 0.70 DRD2 (0.51) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115484948-A Compound and use thereof 福宏治疗公司 2022-12-16 CN disclosed