Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 3/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28816899 | 0.79 | KMT2A (0.43) | MEN1KMT2ATSHRSMN1; SMN2HPGDS | |
| SCHEMBL28284688 | 0.78 | CCNC (0.43) | MEN1KMT2AHPGDTSHRHTT | |
| SCHEMBL28940971 | 0.77 | MMP13 (0.37) | MEN1KMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL28941110 | 0.77 | CFTR (0.38) | HPGDTSHR | |
| SCHEMBL28940917 | 0.77 | CFTR (0.38) | HPGDTSHR | |
| SCHEMBL28940978 | 0.77 | SCN9A (0.39) | — | |
| SCHEMBL28941018 | 0.75 | MEN1 (0.37) | MEN1KMT2AHPGDSMN1; SMN2PARP1 | |
| SCHEMBL459076 | 0.75 | KMT2A (0.43) | MEN1KMT2AHPGDSMN1; SMN2NNMT | |
| SCHEMBL24655828 | 0.75 | P2RX7 (0.39) | PLK1P2RX7PARP1BAZ2BMAP4K1 | |
| SCHEMBL29224909 | 0.75 | RAF1 (0.46) | HPGDTSHRHTTSMN1; SMN2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |