Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497771 | 0.85 | PNMT (0.48) | PNMTLOXL2TAAR1DPP4ALDH1A1 | |
| SCHEMBL234202 | 0.80 | TSHR (0.39) | PNMTTAAR1ALDH1A1TSHRIDO1 | |
| SCHEMBL5399463 | 0.80 | PNMT (0.52) | PNMTLOXL2TAAR1DPP4HTR2A | |
| Iodide SCHEMBL28723808 | 0.78 | PNMT (0.50) | PNMTLOXL2TAAR1DPP4HTR2A | |
| SCHEMBL7865281 | 0.76 | PNMT (0.56) | PNMTLOXL2TAAR1DPP4ALDH1A1 | |
| SCHEMBL2554785 | 0.74 | GABRA1 (0.50) | PNMTLOXL2TAAR1 | |
| SCHEMBL18550415 | 0.74 | ALDH1A1 (0.35) | PNMTALDH1A1TSHR | |
| SCHEMBL6908927 | 0.74 | GABRA1 (0.44) | PNMTTAAR1ALDH1A1TSHRHTR2A | |
| SCHEMBL11643538 | 0.72 | PNMT (0.39) | PNMTTAAR1ALDH1A1TSHRIDO1 | |
| SCHEMBL1539462 | 0.72 | TAAR1 (0.44) | PNMTTAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677598-B | Preparation method for synthesizing pyrimidinedione compound | 南通常佑药业科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-115677598-A | Preparation method for synthesizing pyrimidinedione compound | 南通常佑药业科技有限公司 | 2023-02-03 | — | — | CN | disclosed |