Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30231213 | 1.00 | KIF11 (0.53) | KIF11NOTUMGABRA1GABRG2GABRB3 | |
| SCHEMBL30208027 | 0.87 | TAS1R3 (0.48) | KIF11NOTUMGABRA1GABRG2GABRB3 | |
| SCHEMBL3830811 | 0.83 | NOTUM (0.69) | KIF11NOTUMKCNQ3KCNQ2KCNE1 | |
| SCHEMBL4208340 | 0.83 | CES2 (0.53) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL30208191 | 0.83 | CES2 (0.53) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL13529945 | 0.83 | NOTUM (0.48) | KIF11NOTUMGABRA1GABRG2GABRB3 | |
| SCHEMBL27490413 | 0.83 | ALOX15 (0.48) | KIF11NOTUMGABRA1GABRG2GABRB3 | |
| SCHEMBL29157367 | 0.82 | GABRA1 (0.43) | NOTUMGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL23866225 | 0.81 | NOTUM (0.56) | NOTUMGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4816280 | 0.80 | HDAC1 (0.53) | NOTUMGABRA1GABRG2GABRB3GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |