Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 10/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27894247 | 0.73 | PTGER1 (0.41) | PTGER1RXRARXRBRXRGMCL1 | |
| SCHEMBL28712291 | 0.66 | KMT2A (0.34) | L3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL30008122 | 0.65 | PTGER1 (0.64) | PTGER1RXRARXRBRXRGMCL1 | |
| SCHEMBL29273233 | 0.65 | L3MBTL1 (0.38) | L3MBTL1MAPTKMT2AKDM4E | |
| SCHEMBL26013299 | 0.64 | MAPT (0.63) | PTGER1RXRARXRBRXRGMCL1 | |
| Acetic Acid SCHEMBL5690407 | 0.62 | RXRA (0.72) | PTGER1RXRARXRBRXRGMCL1 | |
| SCHEMBL28688753 | 0.62 | MAOA (0.30) | — | |
| SCHEMBL11112000 | 0.62 | L3MBTL1 (0.52) | PTGER1RXRARXRBRXRGMCL1 | |
| SCHEMBL2305236 | 0.61 | NPC1 (0.68) | L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL4370622 | 0.61 | MAPT (0.50) | RXRAPPIAL3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107021928-B | Eltrombopag intermediate, preparation method and application thereof | 常州制药厂有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-107021928-B | Eltrombopag intermediate, preparation method and application thereof | 常州制药厂有限公司 | 2022-11-18 | — | — | CN | disclosed |