SCHEMBL29273233

SCHEMBL29273233

COc1ccccc1C1=CC(C(=O)O)=CC(C(=O)O)([N+](=O)[O-])C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PTGS2 P35354 1/20 0.35
MAPT P10636 2/20 0.33
DHODH Q02127 2/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
EIF4E P06730 1/20 0.33
GPR35 Q9HC97 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29273234 0.82
SCHEMBL6849472 0.79 L3MBTL1 (0.36) L3MBTL1ALDH1A1TDP1KDM4EHPGD
SCHEMBL28767052 0.70
SCHEMBL28789053 0.70 ALDH1A1 (0.36) L3MBTL1ALDH1A1TDP1KDM4EHPGD
SCHEMBL6852957 0.64 ALDH1A1 (0.31) ALDH1A1HPGDHSD17B10HTT
SCHEMBL6850842 0.63 KDM4E (0.41) L3MBTL1ALDH1A1TDP1KDM4EHPGD
SCHEMBL29574585 0.62 PKM (0.51) L3MBTL1ALDH1A1TDP1KDM4EHPGD
SCHEMBL6850845 0.62 KDM4E (0.40) L3MBTL1ALDH1A1TDP1KDM4EHPGD
SCHEMBL8876243 0.59 ALDH1A1 (0.50) L3MBTL1ALDH1A1TDP1KDM4EHPGD
SCHEMBL8403658 0.59 EIF4E (0.53) L3MBTL1ALDH1A1TDP1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024280-A Efficient yeast dehydrogenase inhibitor 苏州君叶生物医药科技有限公司 2023-11-10 CN disclosed