SCHEMBL28949219

SCHEMBL28949219

COC(=O)Cc1ccc[n+](Cc2cc(OC)cc(OC)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH1A1 P00352 3/20 0.40
THRB P10828 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MMP13 P45452 1/20 0.39
HSP90AB1 P08238 1/20 0.39
SLC7A5 Q01650 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL26087231 0.91 PDK2 (0.37) L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL26414135 0.86 L3MBTL1 (0.46) L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL26414339 0.85 L3MBTL1 (0.52) L3MBTL1ALDH1A1SLC7A5NPSR1HPGD
Trifluoroacetic Acid SCHEMBL30216955 0.80 L3MBTL1 (0.40) L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1
Formic Acid SCHEMBL26087463 0.79 NPSR1 (0.47) L3MBTL1ALDH1A1SLC7A5NPSR1HPGD
SCHEMBL23351211 0.77 PKM (0.40) L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL348963 0.76 HSP90AB1 (0.62) L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL31249652 0.74 SMN1; SMN2 (0.61) SMN1; SMN2MEN1KMT2AALDH1A1MMP13
SCHEMBL378705 0.74 SMN1; SMN2 (0.61) SMN1; SMN2MEN1KMT2AALDH1A1MMP13
SCHEMBL23351010 0.73 ALDH1A1 (0.37) L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667220-A Benzyl pyridinium reagent for mass spectrum 豪夫迈·罗氏有限公司 2023-01-31 CN disclosed