Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714989 | 0.87 | ALDH1A1 (0.44) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL70665 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KMT2ASMN1; SMN2NLRP3PSMB8 | |
| SCHEMBL20463167 | 0.78 | KMT2A (0.35) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL18122756 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL28168374 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL12261668 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL12804228 | 0.76 | HPGD (0.35) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL2581743 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL21385131 | 0.76 | ADORA3 (0.35) | ALDH1A1HPGDGSK3AGSK3BKMT2A | |
| SCHEMBL209163 | 0.76 | DGKA (0.44) | ALDH1A1CYP1A2HPGDCYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108633278-B | Amyloid conjugates and uses and methods thereof | 艾拉科隆生物技术公司 | 2022-09-13 | — | — | CN | disclosed |