Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12968247 | 0.84 | BRD4 (0.49) | CXCL8NOD1HTR6CA12CA2 | |
| SCHEMBL7014825 | 0.83 | CA12 (0.55) | CXCL8NOD1HTR6CA12CA2 | |
| SCHEMBL17422757 | 0.82 | PPARG (0.60) | PPARGPPARAPPARD | |
| SCHEMBL17422837 | 0.82 | ACLY (0.46) | NOD1HTR6CA12CA2CA9 | |
| SCHEMBL17422770 | 0.82 | HTR6 (0.42) | CXCL8NOD1HTR6CA12CA2 | |
| SCHEMBL15747081 | 0.79 | ACLY (0.47) | HTR6CA12CA2CA9PPARG | |
| SCHEMBL32670738 | 0.79 | PPARG (0.60) | NOD1HTR6CA12CA2CA9 | |
| SCHEMBL28952978 | 0.78 | NOD1 (0.47) | NOD1CA12CA2CA9SRC | |
| SCHEMBL1772184 | 0.76 | NOD1 (0.43) | CXCL8NOD1HTR6CA12CA2 | |
| SCHEMBL21147084 | 0.75 | ALDH1A1 (0.41) | CXCL8NOD1HTR6CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677722-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2023-02-03 | — | — | CN | disclosed |