Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1773798 | 0.79 | ALDH1A1 (0.45) | NOD1NOD2ALDH1A1PKMKMT2A | |
| SCHEMBL7014825 | 0.78 | CA12 (0.55) | NOD1NOD2ALDH1A1KMT2ALMNA | |
| SCHEMBL28952979 | 0.78 | CXCL8 (0.46) | NOD1NOD2ALDH1A1KMT2ALMNA | |
| SCHEMBL17422757 | 0.78 | PPARG (0.60) | — | |
| SCHEMBL17422770 | 0.78 | HTR6 (0.42) | NOD1PKMKMT2ALMNAMEN1 | |
| SCHEMBL17422837 | 0.78 | ACLY (0.46) | NOD1NOD2PKMKMT2AMEN1 | |
| SCHEMBL2512172 | 0.76 | HTR6 (0.62) | ALDH1A1PKMKMT2ALMNAMEN1 | |
| SCHEMBL32670738 | 0.75 | PPARG (0.60) | NOD1HTTCA12CA2CA9 | |
| SCHEMBL15747081 | 0.75 | ACLY (0.47) | ALDH1A1KMT2ALMNAMEN1HPGD | |
| SCHEMBL29771205 | 0.74 | GLS (0.52) | NOD1CYP19A1ALDH1A1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677722-A | Compounds targeting p53 mutants | 北京加科思新药研发有限公司 | 2023-02-03 | — | — | CN | disclosed |