Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865487 | 0.88 | HPGD (0.77) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL28958701 | 0.85 | HPGD (0.59) | HPGDSMN1; SMN2ALDH1A1MAPTTHRB | |
| SCHEMBL28958700 | 0.84 | ALDH1A1 (0.73) | HPGDSMN1; SMN2ALDH1A1MAPTTDP1 | |
| SCHEMBL430687 | 0.83 | HPGD (1.00) | HPGDSMN1; SMN2ALDH1A1MAPTTHRB | |
| SCHEMBL28958730 | 0.81 | NPC1 (0.74) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL29944827 | 0.81 | L3MBTL1 (0.57) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL28958706 | 0.80 | HPGD (0.75) | HPGDSMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL25046023 | 0.80 | HPGD (0.67) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL18511929 | 0.80 | HPGD (0.67) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL22289268 | 0.78 | HPGD (0.63) | HPGDSMN1; SMN2ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115707699-A | Anti-osteoporosis compound and application thereof | 中国医学科学院医药生物技术研究所 | 2023-02-21 | — | — | CN | disclosed |