Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.35 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 2/20 | 0.35 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28889335 | 0.90 | ADRB2 (0.38) | ADRB2LMNAPOLBKDRCNR2 | |
| SCHEMBL28959166 | 0.85 | MEN1 (0.41) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL29893755 | 0.83 | MEN1 (0.44) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL28889250 | 0.83 | MEN1 (0.44) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL28889179 | 0.83 | KMT2A (0.41) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL29941697 | 0.82 | MEN1 (0.49) | MEN1KMT2AADRB2POLBCHIT1 | |
| SCHEMBL28889178 | 0.82 | HDAC4 (0.43) | MEN1KMT2AADRB2LMNARIPK2 | |
| SCHEMBL28889186 | 0.81 | MEN1 (0.44) | MEN1KMT2AADRB2LMNAPOLB | |
| SCHEMBL28889385 | 0.81 | NR3C2 (0.40) | ADRB2CNR2AURKAKMONR3C2 | |
| SCHEMBL28889187 | 0.80 | MEN1 (0.40) | MEN1KMT2AADRB2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222911-A1 | PYRIMIDONE COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-10-27 | — | — | WO | disclosed |