Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP12 | P39900 | 4/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 4/20 | 0.36 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28959889 | 0.86 | MEN1 (0.37) | MMP2MMP9MMP12FFAR1MME | |
| SCHEMBL20528865 | 0.79 | MMP2 (0.42) | MMP2MMP9MMP12MAPT | |
| SCHEMBL20528868 | 0.79 | MMP2 (0.42) | MMP2MMP9MMP12MAPT | |
| SCHEMBL21876310 | 0.62 | MMP2 (0.37) | MMP2MMP9MMP12FFAR4FFAR1 | |
| SCHEMBL23694457 | 0.62 | CYP2D6 (0.59) | FFAR4FFAR1MMEMMEL1MAPT | |
| SCHEMBL9634012 | 0.60 | PKM (0.49) | — | |
| SCHEMBL24469716 | 0.60 | ALDH1A1 (0.50) | SMN1; SMN2 | |
| SCHEMBL30585539 | 0.60 | ALDH1A1 (0.50) | SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL761111 | 0.60 | HDAC4 (0.48) | FFAR4FFAR1SMN1; SMN2 | |
| SCHEMBL3386393 | 0.60 | PTGS2 (0.50) | FFAR4FFAR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227372-A | Nucleic acid for inhibiting expression of LPA in a cell | 赛伦斯治疗有限责任公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111465694-A | Nucleic acid for inhibiting expression of L PA in cells | 赛伦斯治疗有限责任公司 | 2020-07-28 | — | — | CN | disclosed |