Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 14/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438071 | 0.86 | KDR (0.38) | EPHA2KDREPHB4CHEK1CHEK2 | |
| SCHEMBL8436900 | 0.83 | EPHA2 (0.42) | EPHA2KDREPHB4CHEK1CHEK2 | |
| SCHEMBL8444662 | 0.81 | EPHA2 (0.44) | EPHA2KDREPHB4CHEK1CHEK2 | |
| SCHEMBL6269488 | 0.78 | EGFR (0.42) | — | |
| SCHEMBL3727488 | 0.77 | EGFR (0.49) | KDREPHB4CHEK2KIT | |
| SCHEMBL6266311 | 0.77 | EGFR (0.44) | KDR | |
| SCHEMBL6266570 | 0.76 | EGFR (0.46) | EPHA2KDREPHB4 | |
| SCHEMBL8444635 | 0.76 | EPHA2 (0.36) | EPHA2KDREPHB4KIT | |
| SCHEMBL6268116 | 0.76 | EHMT2 (0.57) | — | |
| SCHEMBL5618725 | 0.75 | EHMT2 (0.51) | EPHA2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955137-A | Combination therapy | 米拉蒂治疗股份有限公司 | 2021-06-11 | — | — | CN | claimed |