SCHEMBL2896264

SCHEMBL2896264

O=C(OC1CC2C=CC1C2)c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.51
HTR2C P28335 2/20 0.45
HTR2B P41595 2/20 0.45
DRD2 P14416 1/20 0.45
ADRA1D P25100 1/20 0.45
HTR2A P28223 1/20 0.45
HTR7 P34969 1/20 0.45
ADRA1A P35348 1/20 0.45
ADRA1B P35368 1/20 0.45
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 6/20 0.40
MAPT P10636 5/20 0.40
HPGD P15428 3/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SRD5A1 P18405 1/20 0.39
CYP1A2 P05177 3/20 0.39
ADRA2A P08913 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6481509 0.95 SRD5A2 (0.45) SRD5A2HTR2CHTR2BDRD2ADRA1D
SCHEMBL6475721 0.93 SRD5A2 (0.40) SRD5A2HTR2CHTR2BDRD2ADRA1D
SCHEMBL12692038 0.80 POLB (0.40) KDM4EALDH1A1LMNAPOLBKMT2A
SCHEMBL2898584 0.80 BCHE (0.45) KDM4EALDH1A1MAPTHPGDNPC1
SCHEMBL6475500 0.80 HTR2B (0.43) HTR2BDRD2HTR7KDM4EALDH1A1
SCHEMBL2899524 0.79 CHRM2 (0.47)
SCHEMBL2839505 0.77 SCN1A (0.47) KDM4EMAPTNPC1RAB9AKMT2A
SCHEMBL2896530 0.76 KMO (0.43) MAPTNPC1RAB9ATDP1
SCHEMBL6474822 0.74 TRPA1 (0.34) KDM4EALDH1A1MAPTHPGDCYP1A2
SCHEMBL4918684 0.73 SRD5A2 (0.66) SRD5A2HTR2CHTR2BDRD2ADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7646457-B2 Liquid crystal display device FUJIFILM CORPORATION (JP) 2010-01-12 US disclosed
US-20070182895-A1 Liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-08-09 US disclosed
US-7101498-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-09-05 US disclosed
US-6846890-B2 Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization JSR CORPORATION (JP) 2005-01-25 US disclosed
US-20040242824-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING OPENING POLYMERIZATION JSR CORPORATION (JP) 2004-12-02 US disclosed
US-20040242823-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-12-02 US disclosed
EP-1459107-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-09-22 EP disclosed
EP-1435350-A1 NORBORNENE DERIVATIVE AND NORBORNENE POLYMER OBTAINED THEREFROM THROUGH RING-OPENING POLYMERIZATION JSR Corporation (JP) 2004-07-07 EP disclosed
WO-2003056365-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2003-07-10 WO disclosed