Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28964892

C1CCOC1.C=C(NC(=O)OCC)C(=O)O

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 4/20 0.36
RECQL P46063 1/20 0.35
RAB9A P51151 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPK1 P28482 1/20 0.34
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
GAA P10253 3/20 0.32
KDM4E B2RXH2 1/20 0.32
THRB P10828 1/20 0.32
MGAM O43451 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132384 0.86 GAA (0.41) TSHRLMNAPOLBALDH1A1L3MBTL1
SCHEMBL10543581 0.84 GAA (0.39) TSHRLMNAPOLBALDH1A1L3MBTL1
Pyridine SCHEMBL29165993 0.74 SMN1; SMN2 (0.42) TSHRLMNAPOLBALDH1A1RAB9A
Methacrylic Acid SCHEMBL9638845 0.72 ALOX15 (0.50) TSHRLMNAPOLBALDH1A1RECQL
SCHEMBL8928249 0.71 ALDH1A1 (0.45) TSHRLMNAALDH1A1L3MBTL1MAPT
Tetrahydrofuran SCHEMBL27801282 0.70 ALDH1A1 (0.62) TSHRLMNAPOLBALDH1A1RECQL
Tetrahydrofuran SCHEMBL26646373 0.70 TSHR (0.50) TSHRLMNAPOLBALDH1A1RECQL
Tetrahydrofuran SCHEMBL28303981 0.70 THRB (0.48) TSHRLMNAPOLBALDH1A1RECQL
SCHEMBL11649713 0.70 ALDH1A1 (0.42) TSHRLMNAPOLBALDH1A1L3MBTL1
SCHEMBL4650635 0.70 ALDH1A1 (0.39) TSHRLMNAALDH1A1L3MBTL1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117020164-A Preparation method of mobile phone data line shell 东莞市凯晟鑫五金电子有限公司 2023-11-10 CN claimed
CN-115537128-B High-elasticity sealing adhesive for USB Type-C connector and preparation method thereof 惠州市杜科新材料有限公司 2023-10-20 CN claimed
CN-117020164-A Preparation method of mobile phone data line shell 东莞市凯晟鑫五金电子有限公司 2023-11-10 CN disclosed
CN-115537128-B High-elasticity sealing adhesive for USB Type-C connector and preparation method thereof 惠州市杜科新材料有限公司 2023-10-20 CN disclosed
CN-115537128-A High-elasticity sealing adhesive for USB Type-C connector and preparation method thereof 惠州市杜科新材料有限公司 2022-12-30 CN disclosed