Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.31 |
| ▸ | SELE | P16581 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CBFB | Q13951 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25187011 | 0.77 | EIF4A3 (0.48) | DAORAB9A | |
| SCHEMBL28090344 | 0.74 | CYP2A6 (0.41) | CYP2A6 | |
| SCHEMBL23932582 | 0.74 | ALOX15 (0.58) | RAB9A | |
| SCHEMBL3144041 | 0.73 | RAB9A (0.48) | CYP2A6MAOARAB9A | |
| SCHEMBL23482394 | 0.73 | CYP2A6 (0.53) | CYP2A6DAOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4960807 | 0.73 | CYP2A6 (0.49) | CYP2A6DAO | |
| SCHEMBL29956508 | 0.70 | CA2 (0.54) | CYP2A6ITKRAB9A | |
| SCHEMBL5828348 | 0.70 | CA2 (0.54) | CYP2A6ITKRAB9A | |
| SCHEMBL4064508 | 0.70 | ALDH1A1 (0.45) | CYP2A6MAOARAB9A | |
| SCHEMBL8313687 | 0.69 | CYP2A6 (0.45) | CYP2A6MAOADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427404-A | Collagen 1 translation inhibitors and methods of use thereof | 艾尼莫生物科技公司 | 2022-12-02 | — | — | CN | disclosed |