Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288460 | 0.86 | CYP1A2 (0.55) | CD274LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL298546 | 0.82 | MAPK1 (0.56) | LMNACYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL289905 | 0.81 | HPGD (0.60) | CYP1A2CYP2D6CYP2C19KDM4EALDH1A1 | |
| SCHEMBL23956927 | 0.74 | CD274 (0.52) | CD274LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL290238 | 0.74 | SMN1; SMN2 (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL289671 | 0.74 | HTR2C (0.57) | LMNAKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21763579 | 0.73 | ERN1 (0.51) | CD274LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14925215 | 0.73 | LMNA (0.56) | CD274LMNACYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL2787018 | 0.72 | SMN1; SMN2 (0.41) | KDM4EALDH1A1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL23956924 | 0.72 | TSHR (0.49) | CD274LMNACYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |