SCHEMBL28967451

SCHEMBL28967451

CCOP(OCC)c1c2ccccc2nn1-c1ccccc1C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
MPO P05164 5/20 0.37
TSHR P16473 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 2/20 0.35
ATM Q13315 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPT P10636 3/20 0.35
MAPK1 P28482 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CASP3 P42574 1/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28967476 0.85 PDE4B (0.41) MPOALDH1A1LMNAL3MBTL1ATM
SCHEMBL28967478 0.85 ALDH1A1 (0.38) MPOTSHRALDH1A1LMNAATM
SCHEMBL28967467 0.82 MPO (0.51) ADORA3ADORA2AMPOALDH1A1L3MBTL1
SCHEMBL28967455 0.81 MPO (0.41) ADORA3ADORA2AMPOTSHRALDH1A1
SCHEMBL28967463 0.78 MPO (0.41) ADORA3ADORA2AMPOTSHRALDH1A1
SCHEMBL28967454 0.78 STAT1 (0.43) MPOLMNAL3MBTL1HTTATM
SCHEMBL28967452 0.77 RAB9A (0.41) ADORA3ADORA2AMPOTSHRLMNA
SCHEMBL28967458 0.77 ESR2 (0.43) ADORA3ADORA2AMPOALDH1A1LMNA
SCHEMBL28967453 0.77 PTGS1 (0.43) MPOALDH1A1ATMKMT2AMAPT
SCHEMBL28967474 0.76 MPO (0.46) ADORA3ADORA2AMPOALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115613060-A Method for synthesizing C-3 phosphorylated 2H-indazole compound by direct electrochemical oxidation 浙江工业大学 2023-01-17 CN disclosed